Physiochemical studies on achatininH, a novel sialic acid-binding lectin
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چکیده
منابع مشابه
Sialic acid binding lectin from Rana catesbeiana oocyte
(cSBL) is known to have anti-tumor activity. cSBL is a multifunctional protein and is recognized as a pyrimidine basespecific ribonuclease. In respect to its ribonuclease activity, cSBL belongs to the RNase A superfamily, and is a very heat-stable enzyme. It retains 100% activity after heating at 100 °C for 5 min. Four RNases have been isolated from the Rana family of frogs, and their primary s...
متن کاملDetection of sialic acid on cultured cells by binding of a lectin from Limax flavus.
(J. Am. Soc. Nephrol. 1992; 3:113-1 15) washed gently in PBS and solubibized in 1 mL/wehl of 0. 1 % sodium dodecyb sulfate (BioRad, Richmond, CA), and the radioactivity was estimated with a gamma counter (LKB-Bnomma, Sweden). To study the effects of fixation, the lectin binding was measured In cells fixed in 95% ethanol. Because the fixed cells could not be solubihizcd completely in sodium dode...
متن کاملBinding studies of a sialic acid-specific lectin from the horseshoe crab Carcinoscorpius rotunda cauda with various sialoglycoproteins.
Interaction of the sialic acid-specific lectin carcinoscorpin with various sialoglycoproteins was studied by using radioiodinated lectin. The binding of carcinoscorpin was dependent not only on sialic acid content but also on the type of glycosidic linkage and form (branched or linear) of the carbohydrate chains. Carcinoscorpin has different classes of binding sites, and binding follows a pheno...
متن کاملCD22, a B cell-specific immunoglobulin superfamily member, is a sialic acid-binding lectin.
The B lymphocyte cell surface receptor CD22 is an adhesion molecule that can mediate binding to several leukocyte subsets. The first CD22 ligand to be identified was the receptor-linked phosphotyrosine phosphatase CD45, but several lines of evidence suggest that CD22 may interact with multiple counter receptors on adjacent lymphocytes. In the present work, we show that in addition to CD45, a so...
متن کاملSiglec-7: a sialic acid-binding lectin of the immunoglobulin superfamily.
The Siglecs are a recently discovered family of sialic acid-binding lectins of the immunoglobulin (Ig) superfamily. We report a molecule showing homology to the six first reported Siglecs, with the closest relationship to Siglec-3(CD33), Siglec-5, and Siglec-6(OBBP-1). The extracellular portion has two Ig-like domains, with the amino-terminal V-set Ig domain including amino acid residues known ...
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ژورنال
عنوان ژورنال: Biochemical Journal
سال: 1989
ISSN: 0264-6021,1470-8728
DOI: 10.1042/bj2570065